マイクロスコープマイクロスコープ

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    • 620X magnification capillaroscope: amazing clarity!
    • 10% deeper depth of field, compared with the previous model.
    • GOKO's unique "non-reflective observation" technique
    • Uses a global shutter: distortion-free image acquisition
    • USB-powered. Direct connection to PC with a single cable
    • Quantification software contributes to medical research and evidence acquisition
    • GOKO, with 70 years of experience in optics, is responsible for the entire process from development, manufacturing, customization, and sales.
    • Can be delivered from Japan to you or the distributor. Contact us.
    • Video signal model GOKO Bscan-Z is also available.
    • 100% MADE IN JAPAN

    *CE Marked: EN61000-6-1:2007 / EN61000-6-3:2007 / A1:2011

    GOKO Imaging Devices Co., Ltd. is an innovative Japanese manufacturer of optical imaging devices with a 70-year history. We develop, manufacture (made in Japan), and even customize our devices. See our historic products which monopolized global market shares.


  • In the past, we could only "Guess" the shape and flow of capillaries. GOKO's capillaroscopes have made it possible to "Visualize" them clearly. And GOKO's software even realizes "Analyze". It contributes to medical research and evidence acquisition worldwide.

    Features

    Amazing clarity with 620x magnification!
    Can change magnification without changing lenses.

    The image is amazingly clear. It achieves 620x magnification (on a 20-inch monitor). Since it adopts an optical zoom, the image is not pixelated by a digital zoom.

    Magnification can be switched immediately between 175x and 620x without changing lenses. This is another reason why GOKO products are highly supported by professionals all over the world.

    Tongue (175X)Tongue (175X)
    Tongue (620X)Tongue (620X)

    Back of the lower lip (620X)Back of the lower lip (620X)
    Scalp (620X)Scalp (620X)

    The depth of field at high magnification has been increased by 10%!

    "Depth of field" refers to the area in front of and behind the subject that appears to be in focus when the subject is in focus.
    The depth of field of GOKO Bscan-ZD at high magnification is even 10% deeper than that of the previous model, allowing you to observe skin capillaries of the whole body even more vividly.


    2 Ways to use: Both fingertip and full-body observation in one unit!

    Stand (standard accessory)

    For nailfold observation. The stand can be moved in three directions to X, Y, and Z. The finger stand is designed for easy placement of fingers and to protect long fingernails as well. Equipped with a unique "camera shake prevention cap".

    Y-axis movement (back and forth movement of the finger rest)Y-axis movement (back and forth movement of the finger rest)
    X-axis movement (left/right movement of finger rest)X-axis movement (left/right movement of finger rest)
    Even for people with long nails. Even for people with long nails.
    Friendly design for easy finger placementFriendly design for easy finger placement

    For the observation of whole-body surfaces other than the nailfolds, an optional camera hand grip and non-reflective cap set are available, providing clear images and stable observation.

    Camera Handgrip (Optional accessory)

    For observation of all body surfaces. Designed to be easy to hold and operate.

    Easy focus and magnification adjustment with one hand. Easy focus and magnification adjustment with one hand
    Blood flow can be observed without putting pressure on the affected area.Blood flow can be observed without putting pressure on the affected area.

    GOKO Bscan capillaroscope series, which boasts of the industry's top sharpness, has sold more than 3,000 units, and has evolved even further.

    You can choose the model that best suits your needs: GOKO Bscan-ZD for those who want to connect directly to a PC, and GOKO Bscan-Z for those who do not want to use a PC or want to connect to both an analog monitor and a PC.

    ModelOutputNo. of pixelsMagnification (Lower/Higher)
    GOKO Bscan-Z NTSC Composite 0.52M 145X, 590X
    GOKO Bscan-ZD USB Digital 1.3M 177X, 620X

    USB-powered. Direct connection to PC with a single cable.

    Can be connected directly to your Windows 10 computer. No power cable or AC adapter is required.

    Images can also be viewed and captured on a Mac; contact us for Mac software support.

    Direct connection to PCDirect connection to PC

    GOKO's unique "non-reflex observation" technique

    GOKO's unique "non-reflex caps" are available to achieve non-reflection observation of skin capillaries. The cap also reduces pressure on capillaries: Natural flow of blood can be observed. An autoclavable non-reflective cap (NRC-AS5) is also available for use in clean fields or under infection prevention measures.

    Using transparent film: With reflection, with contact to observation area
    Using transparent film: With reflection, with contact to observation area
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    Using the non-reflex cap: No reflection, no-contact to observation area
    Using the non-reflex cap: No reflection, no-contact to observation area

    GOKO, with 70 years of experience in optics, is responsible for the entire process from development, manufacturing, customization, and sales.

    GOKO's capillaroscope series are developed, designed, and manufactured in-house at our own factory adjacent to our headquarters in Kawasaki, Japan. We take full responsibility for the development of our products and also provide personalized after-sales services and supports.

    GOKO, with 70 years of experience in optics

    Uses a global shutter: distortion-free, even when shooting a moving subject.

    It is important to have no image distortion in capturing moving subjects.
    General digital microscopes use a ROLLING shutter, but the rolling shutter method exposes each row of pixels sequentially, so there is a slight time difference in the signal readout, which results in a distorted image of the subject.
    On the other hand, our GOKO Bscan-ZD adopts a global shutter. In the global shutter system, all pixels are exposed at the same time, so that even high-speed streams of blood flow can be captured without distortion.

    Comparison of images of running trains

    Taken with a scope equipped with a global shutterTaken with a scope equipped with a rolling shutter
    Taken with a scope equipped with a global shutter Taken with a scope equipped with a rolling shutter

    Reliability recognized by international medical societies

    The GOKO Bscan capillaroscope series and the software GOKO-VIP have been used in international medical papers and presentations:

    Examples:

    • A medical paper, "Real-time assessment of free flap capillary circulation using video-capillaroscopy" by Dr. Chihiro Matsui of the Department of Plastic and Reconstructive Surgery at Juntendo University, Tokyo, Japan, was accepted by the medical journal Plastic and Reconstructive Surgery.
    • A medical paper, "Nailfold capillaroscopic abnormalities in angioedema with eosinophilia." has been published in the international medical journal Allergology International. It was written by Dr. Sayaka Tsuzuki, Dr. Toshihiko Komai, and more, of the Department of Allergy and Rheumatology, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan.
    • An oral presentation, "The Effects of Skin Surface Temperature Change on Capillary Blood Flow Using Video-Capillaroscopy" by Dr. Chihiro Matsui, of the Department of Plastic and Reconstructive Surgery at Juntendo University, Tokyo, Japan, was adopted as "Oral presentation Tier1 acceptance, Top 200 abstract" at the American Society of Plastic Surgeons in 2021.

    From Guess to Visualize, and then Analyze!
    Quantification software contributes to clinical research and evidence acquisition

    Three types software are available to meet your needs.
    The free software GOKO Measure offers 9 measurement functions, scale display, text display, and Excel transfer.
    Two types of optional software are as follows:

    Software GOKO-VIP for the velocity measurement

    Software GOKO Measure Plus for image analysis and measurement
    In addition to 23 different measurement functions, it offers a wide variety of image processing such as panoramic shooting and live superposition functions.

    Comparison of software functions

     GOKO Measure
    (Free measurement software)
    GOKO-VIP
    to measure velocity
    GOKO Measure Plus
    for image analysis and measurement
    Capture still image and video
    2D measurement
    (9 tools)

    (23 tools)
    Velocity measurement
    Export to Excel
    Stick-to-edge function
    Advanced image processing
    (Image tiling, Image overlay position, Auto detection, HDR composition, and more.)

    (Example of Image Tiling)

    Image Tiling of Nailfold Images of 620X
    Image Tiling of Nailfold Images of 620X
    GOKO-VIP for the velocity measurement
    GOKO-VIP for the velocity measurement
    GOKO Measure Plus for advanced image processing / analysis
    GOKO Measure Plus for advanced image processing / analysis

    No driver required; can be used with Zoom and Windows "Camera" applications

    No driver is required. Aside from GOKO's own recommend software, you can share real-time images of capillaries during a remote conversation via Zoom. In addition, images can be viewed with the "Camera" application, which is the standard application of Windows 10.

    Real-time blood flow images shared remotely via Zoom application
    Real-time blood flow images shared remotely via Zoom application
    Example of using Zoom application
    Example of using Zoom application

    For those who do not need to save images and do not use a PC

    The previous model, the GOKO Bscan-Z, is also available. GOKO Bscan-Z can be connected with a dedicated monitor.

  • Sample Videos

    • Scalp capillaries
    • Lip capillaries
    • Nailfold (fingernail) capillaries
    • Tongue capillaries
    • Facial blemishes, melanin and capillaries
    • Skin temperature and capillary flow
    • Capillaries of the dorsal skin of a mouse
    • Rat skeletal muscle capillaries

    Sample Images

    • Scalp capillaries (620X)Scalp capillaries (620X)
    • Lip capillaries (620X)Lip capillaries (620X)
    • Tongue capillaries (175X)Tongue capillaries (175X)
    • Tongue capillaries (620X)Tongue capillaries (620X)
    • Nailfold (fingernail) capillaries (620X)Nailfold (fingernail) capillaries (620X)
    • Facial blemishes, melanin and capillaries (620X)Facial blemishes, melanin and capillaries (620X)
    • Sulci cutis, Crista cutis 1(175X)Sulci cutis, Crista cutis 1(175X)
    • Sulci cutis, Crista cutis 2(175X)Sulci cutis, Crista cutis 2(175X)
    • Rat skeletal muscle capillaries (620X)Rat skeletal muscle capillaries (620X)

    CAUTION:

    * Copying, modifying, reproducing, transmitting, etc. the contents on this site, for whatever purpose, is strictly prohibited without our prior written permission, regardless of the method or intent.

    * Requires oil/gel application to the object surface in observing capillaries.

  • Options

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      GOKO Measure Plus Software

      Provides various image analysis functions and two-dimensional measurement functions. Greatly expands the applicability of clear images with GOKO's microscope.

      More information
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      GOKO-VIP software for the measurement of the velocity of the capillaries

      GOKO-VIP software measures the velocity of the capillaries recorded by the capillaroscope GOKO Bscan-Z.

      More information
    • Non-reflex cap set for the GOKO Bscan-Z
      Non-reflex cap set for the GOKO Bscan-Z

      Enables "non-reflex" capillary observation of the whole body (patent pending). It does not squeeze the capillaries of the site to be observed.

      More information
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      Non-reflex cap NRC-SA5, autoclavable

      Upgraded to a surgical stainless steel version.

      More information
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      Camera Handgrip

      Enables to hold your microscope in one hand, and adjust the focus with your fingertips. It fits in the hand and reduces camera shake for stable observation.

      More information
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      Exclusive stand for the observation of small animals

      Robust stand with a flexible arm that enables stable observation of small animals such as mouse and rat.

      More information
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      USB Foot Switch

      Enable to release the shutter with your foot when shooting.

      More information
    • Oil set for the GOKO Bscan series
      Oil set for GOKO Bscan series

      Five sets of oil (15 ml) for the observation of capillaries by the GOKO Bscan series.

      More information
    • Gel set for the GOKO Bscan series
      Gel set for GOKO Bscan series

      Five sets of gel (15 ml) for the observation of capillaries in the scalp by the GOKO Bscan series.

      More information
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      Glass Calibration Chart

      GOKO's special glass calibration chart used for calibration when measuring 2D dimensions.

      More information
  • Specifications

    Camera Unit

    Model GOKO EV-80ZD
    Image Signal 1/3” CMOS Color Camera 1.3M pixels, Global shutter
    Electronic Shutter Automatic (Can be fixed via the software GOKO Measure)
    Frame Rate 30fps max.
    Focusing Method Adjust by turning the focus ring
    Magnification Lower: approx. 175X, Higher: approx. 620X (on 20-inch monitor)
    Lighting System Direct lighting by high luminosity LED
    Image Output USB 2.0 digital output by USB2.0 (USB Type A Male)
    Power Source DC5V, USB bus power
    Operating Temperature 0~+40℃
    Operating Humidity MAX60%RH (without condensation)
    Dimensions φ45 (external diameter) × 97 (length)mm (except protrusion, without the Focus Cap)
    φ45 (external diameter) ×103 (length)mm (with the Focus Cap)
    Cable Length USB cable 1.5m (USB Type A - USB Micro B)
    Weight 127g (without the cable and the Focus Cap)
    Attachments ① Focus Cap ②Anti-vibration attachment for observing nailfold capillaries ③ Protection Cap ④ USB Cable ⑤ Oil ⑥ Gel ⑦ Case for the GOKO Bscan-Z/ZD (Smaller) ⑧ Software GOKO Measure ⑨Manual
    Location of Manufacture Japan

    Stand Unit

    Model ST-600Z
    Dimensions Base unit: φ120mm, camera holder unit: φ58mm, height 72.5mm
    Weight 250g
    Range of the movement of the Stage Unit 10mm in a crosswise direction
    Range of the movement of the Camera Holder Unit 10mm vertically
    Overall height with the Camera Unit 132mm, except protrusion
    Location of Manufacturer Japan

    * The GOKO Bscan-ZD is not a medical device.
    * Specifications, contents, and appearance of the products are subject to change without prior notice.

  • FAQ

    Q. It seems to be in focus immediately, is it auto focus?

    Manual focus. Since each capillary has a different depth of field, autofocusing may not be able to focus on the point where we want to observe at ultra-high magnification. However, GOKO Bscan-ZD can quickly and accurately focus on any of the many capillaries that exist just under the skin. Especially, the depth of field of GOKO Bscan-ZD is 10% longer than that of the previous generation models, which enables us to observe a wide range of capillaries with different depths. In addition, since the magnification to ultra-high magnification is performed optically rather than digitally, very clear capillary images can be obtained. This optical design enables clear observation of the movement of white blood cells even at ultra-high magnification.


    Q. Is all we can do with the GOKO Bscan-ZD is to observe capillaries?

    As GOKO Bscan-ZD is directly connected to PC, it is possible to save still images and uncompressed movies by using the standard accessory software "GOKO Measure". "GOKO Measure" has various basic 2D measurement tools.
    We also have another software "GOKO-VIP" which can quantify the flow velocity of the videos of capillaries.
    We also offer the software "GOKO Measure Plus", which is highly functional image processing software.


    Q. Can I observe only nailfolds?

    You could observe not only nailfolds, but also every body parts. By removing the camera from the stand, you could observe all parts of the whole-body surface such as the arm, the scalp, the legs, the tongue, the gums, and so on. In those cases, please use the optional Non-reflection cap set to obtain a clearer image without any reflection.
    Optional Autoclavable non-reflex cap is available for use in clean fields.


    Q. Is the camera heavy? I want to use the camera by hand.

    The weight of the camera is only 127g, which is very light, and the compact size of the camera (97mm in length) makes it easy to use for a long time without getting tired. With the optional Camera handgrip, you can get a very stable image when shooting.


    Q. Does the device require regular maintenance?

    No periodic maintenance is required. The camera uses LEDs as its light source, and in principle, there is no need to replace the lighting.


    Q. Do I need any consumables to observe capillaries?

    Oil and gel is essential for the observation. Contact us for details.


    Q. Are there any body parts where capillaries are easy to be observed? Are there any body parts where capillaries are hard to be observed?

    The body parts where the skin is relatively thin, such as fingertips, can be easily observed. On the other hand, the body part whose keratinous are thick, such as heels, might be difficult to be observed.


    Q. My fingers tremble easily. Isn't it difficult to observe the nailfold capillaries due to camera shake?

    The Anti-vibration cap and the stand unit are GOKO's anti-vibration design. They gently secure the fingers and greatly reduces the tremors of fingers without stopping the movement of capillaries. They are standard accessories.


    Q. What is a Non-reflection cap set?

    Non-reflection cap is an optional cap that enables capillary observation without any reflection in the capillary images. It was uniquely designed by GOKO. It is to be mounted in the tip of the camera body.


    Q. Do I need a special license to use the GOKO Bscan-ZD?

    No. Since it is not a medical device, anyone can use it without qualifications.


    Q. Is it possible to see the capillaries on the scalp?

    Yes. Frontal, parietal, and occipital areas can all be observed. Clear and non-reflective movie can be obtained by using the optional Non-reflex cap set and Camera handgrip. If you observe a scalp with a lot of hair, use a smaller caliber cap (5φ) from the cap set.


    Q. Is it possible to observe the capillaries even in the oral cavity?

    Yes. Use the Autoclavable non-reflex cap. Apply transparent toothpaste to the glass surface of the non-reflection cap to observe capillaries in the anterior gingiva, mucosa, and tongue. If you use regular Non-reflex cap, not autoclavable one, use a food-grade plastic wrap film to cover the cap after applying transparent toothpaste to the glass to keep cleaness. We recommend the use of rubber bands to prevent wrinkles in the plastic wrap.


    Q. Does the GOKO Bscan-ZD focus at two magnification: lower and higher magnification?

    Yes. Low magnification is 175x and high magnification is 620x. The magnification can be easily changed with the zoom ring.
    At low magnification, it is possible to grasp the overall shape and identify detailed observation points.
    At high magnification, detailed observation of capillaries and blood flow can be easily and clearly performed.
    (Note) The magnification is based on a 20-inch monitor, so the magnification will be even higher on a monitor larger than 20 inches.


    Q. What is the effect of oil?

    Oil or gel is essential for the observation of the capillaries just below the dermis of the skin. Contact us for further clarification.


    Q. What should I do when I found partial reflection in observing nailfold capillaries?

    When you use the camera with the stand unit, you can avoid partial reflections by bending the tip of your finger slightly downward. When you use the camera as a handheld camera, please use the optional Anti-reflection cap set.


    Q. Is it possible to observe skin texture?

    Yes. You can easily observe skin texture as well by using the attached focus cap without applying oil or gel. The GOKO Bscan-ZD is also widely used for the research on the relation between skin texture and skin capillaries.


    Q. Is it possible to measure the size of capillaries?

    Measurements can be made with the supplied free measurement software "GOKO Measure" and the optional measuring software "GOKO Measure Plus".


    Q. Which finger is commonly used to observe nailfold capillaries?

    Generally, the ring finger of the non-dominant hand is recommended to be observed. It is said that the nailfold skin of the ring finger of the non-dominant hand is the thinnest and thus the capillaries there are easy to be observed. However, choose another finger depending on individual conditions. In some protocols, it is recommended to observe eight fingers except the thumbs.


    Q. Is it possible to observe at another magnification that is different from the standard specification?

    Yes. We accept customization from one unit. Feel free to contact us if you have any special requests such as observing at higher magnification, changing the shape of the scope, or increasing numbers of pixels.


    Q. What are the merits of the GOKO Bscan-ZD?

    1. 620X magnification capillaroscope: amazing clarity!
    2. 10% deeper depth of field, compared with the previous model.
    3. GOKO's unique "non-reflective observation" technique.
    4. Uses a global shutter: distortion-free image acquisition.
    5. USB-powered. Direct connection to PC with a single cable.
    6. Quantification software contributes to medical research and evidence acquisition.
    7. Standard accessory stand: Adjustable in both XYZ directions, with anti-shake function, and even suitable for people with long nails.
    8. Lightweight: 127g (when used as a handheld, only the camera part is used)
    9. GOKO, with 70 years of experience in optics, is responsible for the entire process from development, manufacturing, customization, and sales.
    10. 100% MADE IN JAPAN

    Q. Tell me about the facilities and applications where it is being used.

    In the medical field, our device is widely known by the terms "capillaroscopy" and "Nailfold Video Capillaroscopy (NVC)," and is used in a wide range of fields, including internal medicine, plastic surgery, orthopedics, dermatology, emergency centers, and rehabilitation departments at university medical schools, affiliated hospitals, and public and private hospitals, as well as pharmacy departments and pharmaceutical companies.
    In the field of health, it is widely used in acupuncture and moxibustion clinics, fitness clubs, health food manufacturers, health appliances, functional water, hydrogen, etc. to confirm the effects of treatments and equipment.
    In the beauty field, the system is used to visualize the effects of cosmetics manufacturers, esthetic salons, and beauty clinics.


    Q. What is the meaning of the term "microcirculation"?

    It refers to the blood circulation in microvasculature, i.e., micro-arteries, capillaries, micro-veins, and arteriovenous anastomoses. Although not all the microcirculation can be observed, the GOKO Bscan series enables us to estimate the body functions and health conditions by observing the microcirculation in every part of the skin surface.


    Q. I would like to observe skin blemishes on my face in addition to the nailfold area.

    Yes. Use the optional Non-reflex cap and Camera handgrip. Apply gel or oil to the glass surface for observation, and you can obtain clear, non-reflective video of blemishes and skin capillaries. Both skin spots, melanin and capillaries can be observed clearly.

    See: https://youtu.be/UVhmB-wBYKg and https://youtu.be/9YUYvgBwkCM

    The mechanism of skin blemishes (an example of senile pigmentation) is due to an imbalance in the production and discharge of melanin in the skin caused by a disturbance in the skin turnover, which is a cyclical function in which new cells produced in the lower part of the epidermis reach the stratum corneum at the top surface and are peeled off as plaque, resulting in an abnormal accumulation of melanin in the epidermis. This is due to the abnormal accumulation of melanin in the epidermis. It is said that where there are many capillaries, factors that stimulate the production of melanin are produced, which activates the spots.